Alcohol doesn't often get billed as brain food, but new research suggests that…

2024

Alcohol doesn't often get billed as brain food, but new research suggests that booze offers at least one cerebral benefit. It may reduce aging drinkers’ risk of developing Alzheimer's disease and other forms of dementia.

Although extreme alcohol consumption kills brain cells, there's contradictory evidence about whether long-term drinking has permanent effects on cognitive abilities such as reasoning and memory. Prolonged, excessive drinking can lead to liver disease cirrhosis and may contribute to breast cancer risk, however. Drinking is also responsible for many accidental injuries and deaths.

Nevertheless, alcohol in moderation promotes cardiovascular health by boosting concentrations of good cholesterol and inhibiting the formation of dangerous blood clots . Additional compounds in red wine seem to benefit the heart and blood vessels . Drinking also appears to guard against macular degeneration, an incurable eye disease.

Now, the brain joins the list of organs that seem to benefit from alcohol.

From 1990 to 1999, Monique M.B. Breteler and her colleagues at the Erasmus Medical Centre in Rotterdam, the Netherlands, observed 5,395 individuals age 55 and older who didn't initially show signs of dementia. Of these participants, 1,443 “moderate drinkers" reported having one to three alcohol beverages of some sort each day, while 2,674 said they consumed less than one drink and 165 acknowledged having four or more drinks per day. Another 1,113 participants abstained altogether.

Over an average follow-up period of 6 years, 146 participants developed Alzheimer's disease and another 51 got some other form of age-related dementia. That put the overall risk for dementia at 3.7 percent. The risk was about 4 percent among non-drinkers, light drinkers, and heavy drinkers, but only 2.6 percent of the moderate drinkers developed dementia.

Once the researchers adjusted their data to account for participants’ sex, age, weight, blood pressure, use of tobacco, and other factors that influence dementia, moderate drinkers showed only 58 percent the risk of dementia calculated for non-drinkers, Breteler's team reported.

Moderate drinkers had an even more marked decrease in vascular dementia, a condition in which blockages in blood vessels in the brain cause recurring, minor strokes that gradually erode cognitive ability. The researchers hypothesize that since vascular disorders are linked to dementia in elderly people, alcohol's benefits to blood vessels might indirectly sustain brain function.

Jean-Marc Orgagozo, a neurological epidemiologist at the University of Bordeaux in France hails the study. He and his colleagues have found that French wine drinkers over the age of 65 have a reduced risk of dementia. The new research supports that finding, shows that beer and hard liquor—not just wine—are protective, and establishes the effect in somewhat younger people, he says.

John R. Copeland, a psychiatrist who's retired from the University of Liverpool in England, calls the Dutch finding "very interesting but not unexpected." Although Copeland's research suggested that heavy, long-term drinking reduces cognitive ability in elderly men, people who show benefits in the new study consumed alcohol in more modest, “therapeutic quantities,” he says.

However, Orgogoze questions exactly what quantity constitutes a happy-hour medium. His own past research suggests three to four drinks per day are required to help ward off dementia. The lower threshold for benefit in the Dutch study may reflect participants’ under-reporting of alcohol consumption in a country that, unlike France, attaches a stigma to drinking, Orgogozo says.

The observations of M.B. Breteler do not include which one of the following?

  1. A.

    Alcohol is highly beneficial for brain function

  2. B.

    all of these

  3. C.

    vascular disorders are linked to dementia in elderly people

  4. D.

    Moderate drinking reduces the risks of vascular dementia

Attempted by 1 students.

Show answer & explanation

Correct answer: A

Concept: In a passage-based Not-Included/Cannot-Say question, only a claim the passage itself states (directly, or as a hypothesis the passage explicitly voices) counts as an included observation. A claim that broadens or overstates what the passage says — even if it sounds plausible — is the one that is NOT included.

Application: The passage states moderate drinkers had a more marked decrease in vascular dementia, and separately reports the researchers' own hypothesis that vascular disorders are linked to dementia in elderly people — both are directly voiced observations. But the passage only credits alcohol with at least one specific cerebral benefit, and explicitly notes contradictory evidence on long-term cognitive effects; it never claims alcohol is broadly or highly beneficial for brain function.

  • Moderate drinking reduces the risks of vascular dementia — directly stated ("an even more marked decrease in vascular dementia"), so it IS an observation.

  • Vascular disorders are linked to dementia in elderly people — directly stated as the researchers' hypothesis, so it IS an observation.

  • Alcohol is highly beneficial for brain function — overstates the passage's narrow, specific benefit language and ignores its explicit contradictory-evidence caveat, so it is NOT an observation.

Cross-check: Since one listed statement is not supported, the option grouping every statement together also cannot hold. Re-reading the passage's own qualifiers ("at least one cerebral benefit", "contradictory evidence") confirms the general brain-function claim is the one excluded from the study's actual observations.

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